Michaël Facompré

Lamellarin D: a novel potent inhibitor of topoisomerase I.

Michaël Facompré, Christelle Tardy, Christine Bal-Mahieu et al. · PubMed · 2003 · 192 citations

Drug Target, Lamellarin D, Chemical Biology +16

Specific inhibition of serine- and arginine-rich splicing factors phosphorylation, spliceosome assembly, and splicing by the antitumor drug NB-506.

Birgit Pilch, Eric Allemand, Michaël Facompré et al. · PubMed · 2001 · 131 citations

Molecular Biology, P388 Cells, Cancer Biology +19

Topoisomerase I-mediated DNA cleavage as a guide to the development of antitumor agents derived from the marine alkaloid lamellarin D: triester derivatives incorporating amino acid residues

Christelle Tardy, Michaël Facompré, William Laine et al. · Bioorganic & Medicinal Chemistry · 2004 · 104 citations

Medicinal Chemistry, Antitumor Agents, Natural Sciences +10

Distribution of Furamidine Analogues in Tumor Cells:  Influence of the Number of Positive Charges

Amélie Lansiaux, Laurent Dassonneville, Michaël Facompré et al. · Journal of Medicinal Chemistry · 2002 · 68 citations

Combinatorial Chemistry, Bioorganic Chemistry, Tumor Cells +16

Relation between intracellular acidification and camptothecin-induced apoptosis in leukemia cells

Jean‐François Goossens, Jean-Pierre Hénichart, Laurent Dassonneville et al. · European Journal of Pharmaceutical Sciences · 2000 · 56 citations

Malignant Blood Disorder, Apoptosis, Cell Death +8