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Topoisomerase I-mediated DNA cleavage as a guide to the development of antitumor agents derived from the marine alkaloid lamellarin D: triester derivatives incorporating amino acid residues

Medicinal ChemistryAntitumor AgentsNatural SciencesMedicineMolecular BiologyTriester DerivativesAmino Acid ResiduesAnti-cancer AgentChemical BiologyPharmacologyPharmaceutical ChemistryDrug DiscoveryDrug Resistance