Disrupted in Schizophrenia 1 Regulates Neuronal Progenitor Proliferation via Modulation of GSK3β/β-Catenin Signaling

Yingwei Mao, Xuecai Ge, Christopher L. Frank, +12

Cell

Gsk3β/β-catenin SignalingDevelopmental BiologyMolecular NeuroscienceSchizophrenia 1Psychiatric Genetics +10

Epigenetic Characterization of the FMR1 Gene and Aberrant Neurodevelopment in Human Induced Pluripotent Stem Cell Models of Fragile X Syndrome

Steven D. Sheridan, Kraig M. Theriault, Surya A. Reis, +5

PLoS ONE

PKC-1 regulates secretion of neuropeptides

Derek Sieburth, Jon M. Madison, Joshua M. Kaplan

Nature Neuroscience

Molecular PhysiologySignal TransductionPhysiologyNeuropeptide ReceptorMolecular Neurobiology +4

Combining NGN2 Programming with Developmental Patterning Generates Human Excitatory Neurons with NMDAR-Mediated Synaptic Transmission

Ralda Nehme, Emanuela Zuccaro, Sulagna Ghosh, +18

Cell Reports

:Gfp Reporter GeneDevelopmental Cognitive NeuroscienceSynaptic TransmissionNeurotransmitterNmdar-mediated Synaptic Transmission +18

The MicroRNA miR-1 Regulates a MEF-2-Dependent Retrograde Signal at Neuromuscular Junctions

David Simon, Jon M. Madison, Annie L. Conery, +5

Cell

Molecular NeuroscienceMolecular PhysiologyMicrorna Mir-1NeuroscienceMef-2-dependent Retrograde Signal +9

Characterization of bipolar disorder patient-specific induced pluripotent stem cells from a family reveals neurodevelopmental and mRNA expression abnormalities

Jon M. Madison, Fangjian Zhou, Aparna Nigam, +22

Molecular Psychiatry

Mrna Expression AbnormalitiesEmbryonic Stem CellInduced Pluripotent Stem CellDevelopmental BiologyMedicine +10

Functional implications of a psychiatric risk variant within CACNA1C in induced human neurons

Takao Yoshimizu, Jen Q. Pan, Alison E. Mungenast, +8

Molecular Psychiatry

Induced Human NeuronsPsychiatryNeuroanatomyNeurotransmitterPsychiatric Risk Variant +9

Dysregulation of miR-34a links neuronal development to genetic risk factors for bipolar disorder

Sabine Bavamian, Nikolaos Mellios, Jasmin Lalonde, +10

Molecular Psychiatry

PsychiatryMedicineGeneticsPsychiatric GeneticsNon-coding Rna +8

Antagonistic Regulation of Synaptic Vesicle Priming by Tomosyn and UNC-13

Jason M. McEwen, Jon M. Madison, Michael Dybbs, +1

Neuron

Synaptic PlasticityProtein SecretionDevelopmental BiologyMolecular NeuroscienceMolecular Physiology +11

An RNAi Screen Identifies Genes that Regulate GABA Synapses

Amy B. Vashlishan, Jon M. Madison, Mike Dybbs, +5

Neuron

Synaptic PlasticityMolecular NeuroscienceSynaptic TransmissionRegulate Gaba SynapsesMolecular Neurobiology +3