Organoids Model Transcriptional Hallmarks of Oncogenic KRAS Activation in Lung Epithelial Progenitor Cells

Antonella F. M. Dost, Aaron L. Moye, Marall Vedaie, +23

Cell stem cell

Transcriptional RegulationDevelopmental BiologyOncogenic Kras ActivationBronchial NeoplasmGene Expression +4

Actionable Cytopathogenic Host Responses of Human Alveolar Type 2 Cells to SARS-CoV-2

Ryan Hekman, Adam J. Hume, Raghuveera Kumar Goel, +47

Molecular Cell

Host ResponseViral PathogenesisImmunologyAntiviral ResponseMedicine +2

Patient-specific iPSCs carrying an SFTPC mutation reveal the intrinsic alveolar epithelial dysfunction at the inception of interstitial lung disease

Konstantinos–Dionysios Alysandratos, Scott J. Russo, Anton Petcherski, +24

Cell Reports

BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain

Mohammad Reza Pourhaghighi, Peter E.A. Ash, Sadhna Phanse, +32

Cell Systems

Dengue Virus Infection of Aedes aegypti Alters Extracellular Vesicle Protein Cargo to Enhance Virus Transmission

Alexander S. Gold, Fabiana Feitosa-Suntheimer, Ricardo Vieira Araujo, +5

International Journal of Molecular Sciences

Humanized mice reveal a macrophage-enriched gene signature defining human lung tissue protection during SARS-CoV-2 infection

Devin Kenney, Aoife K. O’Connell, Jacquelyn Turcinovic, +32

Cell Reports

Lung Tissue ProtectionInflammatory Lung DiseaseLung InflammationViral ImmunityViral Pathogenesis +18

Comprehensive Proteomic Analysis of Spider Dragline Silk from Black Widows: A Recipe to Build Synthetic Silk Fibers

Camille Larracas, Ryan Hekman, Simmone Dyrness, +4

International Journal of Molecular Sciences

Biological Mass SpectrometryBlack WidowsPeptide ScienceAnalytical UltracentrifugationComprehensive Proteomic Analysis +16

Recombinant Lloviu virus as a tool to study viral replication and host responses

Adam J. Hume, Baylee Heiden, Judith Olejnik, +22

PLoS Pathogens

Viral ReplicationVirus RescueLloviu VirusMolecular VirologyNeurovirology +12

Triphenyl phosphate is a selective PPARγ modulator that does not induce brite adipogenesis in vitro and in vivo

Stephanie Kim, Nabil Rabhi, Benjamin C. Blum, +5

Archives of Toxicology

Metabolic SyndromeBiochemistryMedicineNatural SciencesPhysiology +8

Proteomic and phosphoproteomic profiling in heart failure with preserved ejection fraction (HFpEF)

María Valero‐Muñoz, Eng Leng Saw, Ryan Hekman, +5

Frontiers in Cardiovascular Medicine