Jason St. Claire

Mismatch Repair Genes Mlh1 and Mlh3 Modify CAG Instability in Huntington's Disease Mice: Genome-Wide and Candidate Approaches

Ricardo Mouro Pinto, Ella Dragileva, Andrew Kirby et al. · PLoS Genetics · 2013 · 258 citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

Msh2 Acts in Medium-Spiny Striatal Neurons as an Enhancer of CAG Instability and Mutant Huntingtin Phenotypes in Huntington’s Disease Knock-In Mice

Marina Kovalenko, Ella Dragileva, Jason St. Claire et al. · PLoS ONE · 2012 · 95 citations · Full text

Life Sciences, Genetics, Neuroscience +17

High resolution time-course mapping of early transcriptomic, molecular and cellular phenotypes in Huntington’s disease CAG knock-in mice across multiple genetic backgrounds

Seth A. Ament, Jocelynn R. Pearl, Andrea Grindeland et al. · Human Molecular Genetics · 2017 · 50 citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

HttQ111/+ Huntington’s Disease Knock-in Mice Exhibit Brain Region-Specific Morphological Changes and Synaptic Dysfunction

Marina Kovalenko, Austen J. Milnerwood, James V. Giordano et al. · Journal of Huntington s Disease · 2018 · 37 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Histone deacetylase knockouts modify transcription, CAG instability and nuclear pathology in Huntington disease mice

Marina Kovalenko, Serkan Erdin, Marissa A Andrew et al. · eLife · 2020 · 21 citations · Full text

Life Sciences, Genetics, Molecular Genetics +17