Marissa A Andrew

Patterns of CAG repeat instability in the central nervous system and periphery in Huntington’s disease and in spinocerebellar ataxia type 1

Ricardo Mouro Pinto, Larissa Arning, James V. Giordano et al. · Human Molecular Genetics · 2020 · 120 citations · Full text

Neurological Disorder, Genetics, Synaptic Signaling +18

Promotion of somatic CAG repeat expansion by Fan1 knock-out in Huntington’s disease knock-in mice is blocked by Mlh1 knock-out

Jacob M. Loupe, Ricardo Mouro Pinto, Kyung‐Hee Kim et al. · Human Molecular Genetics · 2020 · 89 citations · Full text

Somatic Expansion, Knockout Mouse, Genome Instability +13

Somatic CAG expansion in Huntington's disease is dependent on the MLH3 endonuclease domain, which can be excluded via splice redirection

Jennie C. L. Roy, Antonia Vitalo, Marissa A Andrew et al. · Nucleic Acids Research · 2021 · 40 citations · Full text

Mlh3 Endonuclease Domain, Genetics, Molecular Biology +17

Histone deacetylase knockouts modify transcription, CAG instability and nuclear pathology in Huntington disease mice

Marina Kovalenko, Serkan Erdin, Marissa A Andrew et al. · eLife · 2020 · 18 citations · Full text

Huntingtin lowering reduces somatic instability at CAG-expanded loci

Sydney R. Coffey, Marissa A Andrew, Heather Ging et al. · 2020 · 10 citations · Full text

Biomedical Research, Huntingtin Protein, Genetics +19