James V. Giordano

Patterns of CAG repeat instability in the central nervous system and periphery in Huntington’s disease and in spinocerebellar ataxia type 1

Ricardo Mouro Pinto, Larissa Arning, James V. Giordano et al. · Human Molecular Genetics · 2020 · 137 citations · Full text

Life Sciences, Genetics, Neuroscience +17

A patient-derived cellular model for Huntington’s disease reveals phenotypes at clinically relevant CAG lengths

Claudia Lin-Kar Hung, Tamara Maiuri, Laura E. Bowie et al. · Molecular Biology of the Cell · 2018 · 45 citations

Life Sciences, Cell Biology, Genetics +17

Genetic modifiers of somatic expansion and clinical phenotypes in Huntington’s disease highlight shared and tissue-specific effects

Jong‐Min Lee, Zachariah L. McLean, Kevin Correia et al. · Nature Genetics · 2025 · 42 citations · Full text

Life Sciences, Genetics, Molecular Genetics +12

HttQ111/+ Huntington’s Disease Knock-in Mice Exhibit Brain Region-Specific Morphological Changes and Synaptic Dysfunction

Marina Kovalenko, Austen J. Milnerwood, James V. Giordano et al. · Journal of Huntington s Disease · 2018 · 37 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Genetic modifiers of somatic expansion and clinical phenotypes in Huntington’s disease reveal shared and tissue-specific effects

Jong‐Min Lee, Zachariah L. McLean, Kevin Correia et al. · bioRxiv (Cold Spring Harbor Laboratory) · 2024 · 19 citations

Life Sciences, Genetics, Molecular Genetics +17