Jacob M. Loupe

CAG Repeat Not Polyglutamine Length Determines Timing of Huntington’s Disease Onset

Jong‐Min Lee, Kevin Correia, Jacob M. Loupe et al. · Cell · 2019 · 562 citations · Full text

Life Sciences, Genetics, Molecular Genetics +13

Single-cell genomics and regulatory networks for 388 human brains

Prashant S. Emani, Jason Liu, Jason Liu et al. · Science · 2024 · 149 citations · Full text

Life Sciences, Bioinformatics, Neuroscience +17

Promotion of somatic CAG repeat expansion by Fan1 knock-out in Huntington’s disease knock-in mice is blocked by Mlh1 knock-out

Jacob M. Loupe, Ricardo Mouro Pinto, Kyung‐Hee Kim et al. · Human Molecular Genetics · 2020 · 90 citations · Full text

Life Sciences, Genetics, Molecular Genetics +16

Single nucleus multiomics identifies ZEB1 and MAFB as candidate regulators of Alzheimer’s disease-specific cis-regulatory elements

Ashlyn G. Anderson, Brianne B. Rogers, Jacob M. Loupe et al. · Cell Genomics · 2023 · 81 citations · Full text

Life Sciences, Genetics, Molecular Biology +17

Genetic and Functional Analyses Point to FAN1 as the Source of Multiple Huntington Disease Modifier Effects

Kyung‐Hee Kim, Eun Pyo Hong, Jun Wan Shin et al. · The American Journal of Human Genetics · 2020 · 74 citations · Full text

Life Sciences, Genetics, Molecular Genetics +10