Michael P. Agius

Mapping the Degradable Kinome Provides a Resource for Expedited Degrader Development

Katherine A. Donovan, Fleur M. Ferguson, Jonathan W. Bushman et al. · Cell · 2020 · 346 citations · Full text

Geometric Modeling, Robotics, Engineering +11

Single-cell RNA sequencing reveals compromised immune microenvironment in precursor stages of multiple myeloma

Oksana Zavidij, Nicholas J. Haradhvala, Tarek H. Mouhieddine et al. · Nature Cancer · 2020 · 341 citations · Full text

Hematological Malignancy, Single Cell Sequencing, Medicine +14

X-ray Structural and Biological Evaluation of a Series of Potent and Highly Selective Inhibitors of Human Coronavirus Papain-like Proteases

Yahira M. Báez-Santos, Scott J. Barraza, Michael W. Wilson et al. · Journal of Medicinal Chemistry · 2014 · 273 citations · Full text

Highly Selective Inhibitors, Medicinal Chemistry, Homologous Plp2 Enzyme +15

Molecular bottlebrush prodrugs as mono- and triplex combination therapies for multiple myeloma

Alexandre Detappe, Hung V.‐T. Nguyen, Yivan Jiang et al. · Nature Nanotechnology · 2023 · 95 citations · Full text

Hematological Malignancy, Medicine, Pharmacology +11

Pro-organic radical contrast agents (“pro-ORCAs”) for real-time MRI of pro-drug activation in biological systems

Hung V.‐T. Nguyen, Alexandre Detappe, Peter Harvey et al. · Polymer Chemistry · 2020 · 30 citations · Full text