Can Tan

Hrd1 suppresses Nrf2-mediated cellular protection during liver cirrhosis

Tongde Wu, Fei Zhao, Beixue Gao et al. · Genes & Development · 2014 · 341 citations · Full text

Nrf2-mediated Cellular Protection, Lipid Peroxidation, Pathology +20

Toll‐like receptor‐mediated IRE1α activation as a therapeutic target for inflammatory arthritis

Quan Qiu, Ze Zheng, Lin Chang et al. · The EMBO Journal · 2013 · 213 citations · Full text

USP10 Antagonizes c-Myc Transcriptional Activation through SIRT6 Stabilization to Suppress Tumor Formation

Zhenghong Lin, Hee‐Young Yang, Can Tan et al. · Cell Reports · 2013 · 203 citations · Full text

Tumor Biology, Transcriptional Regulation, Cell Regulation +14

USP22 deficiency leads to myeloid leukemia upon oncogenic Kras activation through a PU.1-dependent mechanism

Johanna Melo‐Cardenas, Yuanming Xu, Juncheng Wei et al. · Blood · 2018 · 99 citations · Full text

Ubiquitin-specific protease 22 is a deubiquitinase of CCNB1

Zhenghong Lin, Can Tan, Quan Qiu et al. · Cell Discovery · 2015 · 83 citations · Full text