Pam Gaskin

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Active since

2001

Affiliations

GlaxoSmithKline (United Kingdom)(Current)

Pam Gaskin is an author at GlaxoSmithKline (United Kingdom) specializing in pharmacology, multiple sclerosis therapy, and multiple sclerosis pharmacotherapy.

Publications per year

2001–2016

Publications

Discovery of a Brain-Penetrant S1P3-Sparing Direct Agonist of the S1P1 and S1P5 Receptors Efficacious at Low Oral Dose

Emmanuel H. Demont, Sandra Arpino, Rino A. Bit et al. · Journal of Medicinal Chemistry · 2011 · 35 citations · Full text

Medicine, Neurology, Pharmacology +15

Discovery of a Selective S1P1 Receptor Agonist Efficacious at Low Oral Dose and Devoid of Effects on Heart Rate

Emmanuel H. Demont, Benjamin I. Andrews, Rino A. Bit et al. · ACS Medicinal Chemistry Letters · 2011 · 27 citations

Medicine, Medicinal Chemistry, Pharmacology +13

5-HT, receptor agonists stimulate small intestinal transit but do not have direct visceral antinociceptive effects in the rat

Gareth A. Hicks, Nick M. Clayton, Pam Gaskin et al. · Gastroenterology · 2001 · 11 citations

Medicine, Neuroscience, Pharmacology +14

The utility of pharmacokinetic–pharmacodynamic modeling in the discovery and optimization of selective S1P1agonists

S. Taylor, James R. Gray, Robert Willis et al. · Xenobiotica · 2012 · 10 citations

Pharmacy, Pharmacokinetics, Pharmacology +17

Discovery of Tetrahydropyrazolopyridine as Sphingosine 1-Phosphate Receptor 3 (S1P3)-Sparing S1P1 Agonists Active at Low Oral Doses

Emmanuel H. Demont, James M. Bailey, Rino A. Bit et al. · Journal of Medicinal Chemistry · 2016 · 10 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14

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