Leanna Lagpacan

<i>In vivo</i> Incorporation of Unnatural Amino Acids to Probe Structure, Dynamics, and Ligand Binding in a Large Protein by Nuclear Magnetic Resonance Spectroscopy

Susan E. Cellitti, David H. Jones, Leanna Lagpacan et al. · Journal of the American Chemical Society · 2008 · 192 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +15

Structural, Biochemical, and Biophysical Characterization of Idelalisib Binding to Phosphoinositide 3-Kinase δ

John R. Somoza, David Koditek, Armando G. Villaseñor et al. · Journal of Biological Chemistry · 2015 · 157 citations · Full text

Life Sciences, Biochemistry, Pharmacology +16

Visualizing the Molecular Interactions of a Nucleotide Analog, GS-9148, with HIV-1 Reverse Transcriptase–DNA Complex

E.B. Lansdon, Dharmaraj Samuel, Leanna Lagpacan et al. · Journal of Molecular Biology · 2010 · 48 citations

Life Sciences, Biology, Molecular Biology +12

Inhibition of Hepatitis C Virus Replication by GS-6620, a Potent <i>C</i> -Nucleoside Monophosphate Prodrug

Joy Y. Feng, Guofeng Cheng, Jason K. Perry et al. · Antimicrobial Agents and Chemotherapy · 2014 · 41 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

Structural and Regulatory Elements of HCV NS5B Polymerase – β-Loop and C-Terminal Tail – Are Required for Activity of Allosteric Thumb Site II Inhibitors

S.E. Boyce, Neeraj Tirunagari, Anita Niedziela‐Majka et al. · PLoS ONE · 2014 · 35 citations · Full text

Life Sciences, Molecular Biology, Pharmacology +14