Concepedia

Dorian M. Cheff

DM

15

Publications

1K

Citations

14

H-Index

2017

Active since

Affiliations

National Center for Advancing Translational Sciences(Current)

National Institutes of Health

National Institute of Oncology

Frederick National Laboratory for Cancer Research

University of Pennsylvania

Dorian M. Cheff is an author at National Center for Advancing Translational Sciences specializing in medicine, drug discovery, and pharmacology.

ORCID

Top concepts

Publications per year

2017–2023

15

Publications

15

The ferroptosis inducing compounds RSL3 and ML162 are not direct inhibitors of GPX4 but of TXNRD1

Dorian M. Cheff, Chuying Huang, Karoline Scholzen et al. · Redox Biology · 2023 · 215 citations · Full text

Discovery and Optimization of Potent, Cell-Active Pyrazole-Based Inhibitors of Lactate Dehydrogenase (LDH)

Ganesha Rai, Kyle R. Brimacombe, Bryan T. Mott et al. · Journal of Medicinal Chemistry · 2017 · 146 citations · Full text

Resistance to Epigenetic-Targeted Therapy Engenders Tumor Cell Vulnerabilities Associated with Enhancer Remodeling

Amanda Balboni Iniguez, Gabriela Alexe, Emily Jue Wang et al. · Cancer Cell · 2018 · 91 citations · Full text

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Discovery of Orally Bioavailable, Quinoline-Based Aldehyde Dehydrogenase 1A1 (ALDH1A1) Inhibitors with Potent Cellular Activity

Shyh‐Ming Yang, Natalia J. Martinez, Adam Yasgar et al. · Journal of Medicinal Chemistry · 2018 · 87 citations · Full text

, , +15

High-throughput screening with nucleosome substrate identifies small-molecule inhibitors of the human histone lysine methyltransferase NSD2

Nathan P. Coussens, Stephen C. Kales, Mark J. Henderson et al. · Journal of Biological Chemistry · 2018 · 74 citations · Full text

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