TCA Cycle and Mitochondrial Membrane Potential Are Necessary for Diverse Biological Functions

Inmaculada Martínez‐Reyes, Lauren Diebold, Hyewon Kong, +13

Molecular Cell

MitophagySignal TransductionMitochondrial FunctionBiochemistryTca Cycle +5

The mitochondrial respiratory chain is essential for haematopoietic stem cell function

Elena Ansó, Samuel E. Weinberg, Lauren Diebold, +11

Nature Cell Biology

Mitochondrial Respiratory ChainMitophagyDevelopmental BiologyMitochondrial FunctionMitochondrial Dynamic +8

Targeting SOD1 reduces experimental non–small-cell lung cancer

Andrea Glasauer, Laura A. Sena, Lauren Diebold, +2

Journal of Clinical Investigation

Mitochondrial complex III is necessary for endothelial cell proliferation during angiogenesis

Lauren Diebold, Hyea Jin Gil, Peng Gao, +3

Nature Metabolism

Developmental BiologyAngiogenesisMitochondrial FunctionVascular BiologyMedicine +5

Increased dosage of the chromosome 21 ortholog Dyrk1a promotes megakaryoblastic leukemia in a murine model of Down syndrome

Sébastien Malinge, Meghan Bliss‐Moreau, Gina Kirsammer, +4

Journal of Clinical Investigation

Identification of Regulators of Polyploidization Presents Therapeutic Targets for Treatment of AMKL

Qiang Wen, Benjamin Goldenson, Serena J. Silver, +45

Cell

Cell RegulationReceptor Tyrosine KinaseImmunologyCell ProliferationMedicine +3

Construction of a Sequence-Tagged High-Density Genetic Map of Papaya for Comparative Structural and Evolutionary Genomics in Brassicales

Cuixia Chen, Qingyi Yu, Shaobin Hou, +15

Genetics

Plant GeneticsLinkage MappingBotanyGeneticsLinkage Analysis +14

AKT is a therapeutic target in myeloproliferative neoplasms

Irum Khan, Zan Huang, Qing Wen, +15

Leukemia

Hematological MalignancyMedicineImmunologyOncologyCancer Research +1

DYRK1A controls the transition from proliferation to quiescence during lymphoid development by destabilizing Cyclin D3

Benjamin J. Thompson, Rahul S. Bhansali, Lauren Diebold, +8

The Journal of Experimental Medicine

ER-associated ubiquitin ligase HRD1 programs liver metabolism by targeting multiple metabolic enzymes

Juncheng Wei, Yanzhi Yuan, Lu Chen, +17

Nature Communications