Nyssa Drinkwater

Two-Pronged Attack: Dual Inhibition of <i>Plasmodium falciparum</i> M1 and M17 Metalloaminopeptidases by a Novel Series of Hydroxamic Acid-Based Inhibitors

Shailesh N. Mistry, Nyssa Drinkwater, Chiara Ruggeri et al. · Journal of Medicinal Chemistry · 2014 · 66 citations · Full text

Bioorganic Chemistry, Antiparasitic Agent, Malaria +19

Human immunoglobulin E flexes between acutely bent and extended conformations

Nyssa Drinkwater, Benjamin P. Cossins, Anthony H. Keeble et al. · Nature Structural & Molecular Biology · 2014 · 62 citations · Full text

Extended Conformations, Immunocytochemical Technique, Autoimmune Disease +9

Potent dual inhibitors of Plasmodium falciparum M1 and M17 aminopeptidases through optimization of S1 pocket interactions

Nyssa Drinkwater, Natalie B. Vinh, Shailesh N. Mistry et al. · European Journal of Medicinal Chemistry · 2016 · 62 citations · Full text

Potent Dual Inhibitors, S1 Pocket Interactions, Drug Target +11

Hydroxamic Acid Inhibitors Provide Cross-Species Inhibition of <i>Plasmodium</i> M1 and M17 Aminopeptidases

Natalie B. Vinh, Nyssa Drinkwater, Tess R. Malcolm et al. · Journal of Medicinal Chemistry · 2018 · 47 citations · Full text

Drug Target, Antiparasitic Agent, Malaria +16

Fragment-based screening by X-ray crystallography, MS and isothermal titration calorimetry to identify PNMT (phenylethanolamine N-methyltransferase) inhibitors

Nyssa Drinkwater, Hoan Vu, Kimberly M. Lovell et al. · Biochemical Journal · 2010 · 45 citations