Benjamin P. Cossins

Understanding Cryptic Pocket Formation in Protein Targets by Enhanced Sampling Simulations

Vladimiras Oleinikovas, Giorgio Saladino, Benjamin P. Cossins et al. · Journal of the American Chemical Society · 2016 · 230 citations · Full text

Natural Sciences, Biophysics, Pharmacology +17

Small molecules that inhibit TNF signalling by stabilising an asymmetric form of the trimer

James P. O’Connell, John Porter, Boris Kroeplien et al. · Nature Communications · 2019 · 131 citations · Full text

Medicine, Immunology, Pharmacology +12

Raman Study of Mechanically Induced Oxygenation State Transition of Red Blood Cells Using Optical Tweezers

Satish Rao, Štefan Bálint, Benjamin P. Cossins et al. · Biophysical Journal · 2008 · 108 citations · Full text

Natural Sciences, Biophysics, Physics +14

Allosteric mechanism of action of the therapeutic anti-IgE antibody omalizumab

Anna M. Davies, Elizabeth G. Allan, Anthony H. Keeble et al. · Journal of Biological Chemistry · 2017 · 86 citations · Full text

Life Sciences, Immunology, Pharmacotherapy +14

Exploring Transition Pathway and Free-Energy Profile of Large-Scale Protein Conformational Change by Combining Normal Mode Analysis and Umbrella Sampling Molecular Dynamics

Jinan Wang, Qiang Shao, Zhijian Xu et al. · The Journal of Physical Chemistry B · 2013 · 71 citations

Natural Sciences, Biochemistry, Biophysics +17