Benjamin P. Cossins

Understanding Cryptic Pocket Formation in Protein Targets by Enhanced Sampling Simulations

Vladimiras Oleinikovas, Giorgio Saladino, Benjamin P. Cossins et al. · Journal of the American Chemical Society · 2016 · 221 citations · Full text

Protein Assembly, Cryptic Pocket Formation, Molecular Biology +20

Small molecules that inhibit TNF signalling by stabilising an asymmetric form of the trimer

James P. O’Connell, John Porter, Boris Kroeplien et al. · Nature Communications · 2019 · 120 citations · Full text

Raman Study of Mechanically Induced Oxygenation State Transition of Red Blood Cells Using Optical Tweezers

Satish Rao, Štefan Bálint, Benjamin P. Cossins et al. · Biophysical Journal · 2008 · 107 citations · Full text

Engineering, Spectroscopy, Raman Study +7

Allosteric mechanism of action of the therapeutic anti-IgE antibody omalizumab

Anna M. Davies, Elizabeth G. Allan, Anthony H. Keeble et al. · Journal of Biological Chemistry · 2017 · 84 citations · Full text

Exploring Transition Pathway and Free-Energy Profile of Large-Scale Protein Conformational Change by Combining Normal Mode Analysis and Umbrella Sampling Molecular Dynamics

Jinan Wang, Qiang Shao, Zhijian Xu et al. · The Journal of Physical Chemistry B · 2013 · 70 citations

Protein Assembly, Free-energy Profile, Molecular Biology +21