Concepedia

Melanie Cooke

MC

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Publications

4

Citations

141

H-Index

4

Active since

2015

Affiliations

Amgen (United States)(Current)

Melanie Cooke is an author at Amgen (United States) specializing in molecular pharmacology, pharmacology, and pain neurobiology.

Publications per year

2015–2025

4

Publications

4

Sulfonamides as Selective Na<sub>V</sub>1.7 Inhibitors: Optimizing Potency, Pharmacokinetics, and Metabolic Properties to Obtain Atropisomeric Quinolinone (AM-0466) that Affords Robust in Vivo Activity

Russell F. Graceffa, Alessandro A. Boezio, Jessica Able et al. · Journal of Medicinal Chemistry · 2017 · 69 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

Selective antagonism of TRPA1 produces limited efficacy in models of inflammatory- and neuropathic-induced mechanical hypersensitivity in rats

Sonya G. Lehto, Andy Weyer, Beth D. Youngblood et al. · Molecular Pain · 2016 · 30 citations · Full text

Life Sciences, Neuroscience, Pharmacology +16

Add-On Treatment With Zilebesiran for Inadequately Controlled Hypertension

Akshay S. Desai, Adam Karns, Jolita Badarienė et al. · JAMA · 2025 · 27 citations · Full text

Pharmacy, Pharmacology, Pharmacotherapy +17

Inhibition of Inactive States of Tetrodotoxin-Sensitive Sodium Channels Reduces Spontaneous Firing of C-Fiber Nociceptors and Produces Analgesia in Formalin and Complete Freund’s Adjuvant Models of Pain

David J. Matson, Darryl T. Hamamoto, Howard Bregman et al. · PLoS ONE · 2015 · 15 citations · Full text

Medicine, Neurobiology, Pharmacology +17

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