Paul N. Devine

Biocatalytic Asymmetric Synthesis of Chiral Amines from Ketones Applied to Sitagliptin Manufacture

Christopher K. Savile, Jacob M. Janey, Emily C. Mundorff et al. · Science · 2010 · 1.7K citations

Engineering, Biocatalytic Asymmetric Synthesis, Organic Chemistry +17

Design of an in vitro biocatalytic cascade for the manufacture of islatravir

Mark A. Huffman, Anna Fryszkowska, Oscar Alvizo et al. · Science · 2019 · 601 citations

Enzyme-catalyzed Reactions, Biomanufacturing, Biosynthesis +15

Mass Activated Droplet Sorting (MADS) Enables High‐Throughput Screening of Enzymatic Reactions at Nanoliter Scale

Daniel Holland-Moritz, Michael K. Wismer, Benjamin F. Mann et al. · Angewandte Chemie International Edition · 2019 · 158 citations · Full text

Efficient Synthesis of NK₁ Receptor Antagonist Aprepitant Using a Crystallization-Induced Diastereoselective Transformation

Karel M. J. Brands, Joseph F. Payack, Jonathan D. Rosen et al. · Journal of the American Chemical Society · 2003 · 156 citations

Medicinal Chemistry, Biochemistry, Functional Selectivity +14

Enzyme-Catalyzed Enantioselective Diaryl Ketone Reductions

Matthew D. Truppo, David Pollard, Paul N. Devine · Organic Letters · 2006 · 128 citations