Wing Lee Chan

Deletions, Inversions, Duplications: Engineering of Structural Variants using CRISPR/Cas in Mice

Katerina Kraft, Sinje Geuer, Anja J. Will et al. · Cell Reports · 2015 · 237 citations · Full text

Life Sciences, Biotechnology, Genetics +17

Exome sequencing and CRISPR/Cas genome editing identify mutations of <i>ZAK</i> as a cause of limb defects in humans and mice

Malte Spielmann, Naseebullah Kakar, Naeimeh Tayebi et al. · Genome Research · 2016 · 62 citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

Transport activity and presence of ClC‐7/Ostm1 complex account for different cellular functions

Stefanie Weinert, Sabrina Jabs, Svea Hohensee et al. · EMBO Reports · 2014 · 57 citations · Full text

Life Sciences, Biochemistry, Cell Biology +5

GORAB scaffolds COPI at the trans-Golgi for efficient enzyme recycling and correct protein glycosylation

Tomasz M. Witkos, Wing Lee Chan, Merja Joensuu et al. · Nature Communications · 2019 · 56 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

Impaired proteoglycan glycosylation, elevated TGF-β signaling, and abnormal osteoblast differentiation as the basis for bone fragility in a mouse model for gerodermia osteodysplastica

Wing Lee Chan, Magdalena Steiner, Tomasz M. Witkos et al. · PLoS Genetics · 2018 · 47 citations · Full text

Medicine, Genetics, Molecular Genetics +17