Christine Chabot

Discovery and Preclinical Pharmacology of a Selective ATP-Competitive Akt Inhibitor (GDC-0068) for the Treatment of Human Tumors

James F. Blake, Rui Xu, Josef R. Bencsik et al. · Journal of Medicinal Chemistry · 2012 · 188 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +16

Sterically Biased 3,3-Sigmatropic Rearrangement of Chiral Allylic Azides: Application to the Total Syntheses of Alkaloids

Sophie Lauzon, François Tremblay, David Gagnon et al. · The Journal of Organic Chemistry · 2008 · 85 citations

Pharmacy, Chemistry, Medicinal Chemistry +16

Discovery of Novel PI3-Kinase δ Specific Inhibitors for the Treatment of Rheumatoid Arthritis: Taming CYP3A4 Time-Dependent Inhibition

Brian S. Safina, Stewart Baker, Matt Baumgardner et al. · Journal of Medicinal Chemistry · 2012 · 66 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Potent and Highly Selective Benzimidazole Inhibitors of PI3-Kinase Delta

Jeremy Murray, Zachary K. Sweeney, Bryan Chan et al. · Journal of Medicinal Chemistry · 2012 · 66 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

Design of Conformationally Constrained Acyl Sulfonamide Isosteres: Identification of<i>N</i>-([1,2,4]Triazolo[4,3-<i>a</i>]pyridin-3-yl)methane-sulfonamides as Potent and Selective<i>h</i>Na_V1.7 Inhibitors for the Treatment of Pain

Thilo Focken, Sultan Chowdhury, Alla Zenova et al. · Journal of Medicinal Chemistry · 2018 · 30 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16