Dirk H. Lenz

Femtomolar Transition State Analogue Inhibitors of 5′-Methylthioadenosine/S-Adenosylhomocysteine Nucleosidase from Escherichia coli

Vipender Singh, Gary B. Evans, Dirk H. Lenz et al. · Journal of Biological Chemistry · 2005 · 142 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +15

Syntheses and bio-activities of the l-enantiomers of two potent transition state analogue inhibitors of purine nucleoside phosphorylases

Keith Clinch, Gary B. Evans, George W. J. Fleet et al. · Organic & Biomolecular Chemistry · 2006 · 69 citations

Pharmacy, Medicinal Chemistry, Pharmacology +13

Picomolar Inhibitors as Transition-State Probes of 5′-Methylthioadenosine Nucleosidases

Jemy A. Gutierrez, Minkui Luo, Vipender Singh et al. · ACS Chemical Biology · 2007 · 65 citations · Full text

Life Sciences, Biochemistry, Pharmacology +15

Structure and Inhibition of a Quorum Sensing Target from <i>Streptococcus pneumoniae</i>

Vipender Singh, Wuxian Shi, Steven C. Almo et al. · Biochemistry · 2006 · 62 citations · Full text

Life Sciences, Biochemistry, Microbiology +17

Second Generation Transition State Analogue Inhibitors of Human 5‘-Methylthioadenosine Phosphorylase

Gary B. Evans, Richard H. Furneaux, Dirk H. Lenz et al. · Journal of Medicinal Chemistry · 2005 · 61 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +15