Keith Clinch

Femtomolar Transition State Analogue Inhibitors of 5′-Methylthioadenosine/S-Adenosylhomocysteine Nucleosidase from Escherichia coli

Vipender Singh, Gary B. Evans, Dirk H. Lenz et al. · Journal of Biological Chemistry · 2005 · 139 citations · Full text

Biosynthesis, Quorum Sensing, Biochemistry +13

A Novel Mechanism for Desulfation of Mucin: Identification and Cloning of a Mucin-Desulfating Glycosidase (Sulfoglycosidase) from <i>Prevotella</i> Strain RS2

Jung-hyun Rho, Damian P. Wright, David L. Christie et al. · Journal of Bacteriology · 2005 · 79 citations · Full text

Four generations of transition-state analogues for human purine nucleoside phosphorylase

Meng-Chiao Ho, Wuxian Shi, Agnes Rinaldo-Matthis et al. · Proceedings of the National Academy of Sciences · 2010 · 79 citations · Full text

Syntheses and bio-activities of the l-enantiomers of two potent transition state analogue inhibitors of purine nucleoside phosphorylases

Keith Clinch, Gary B. Evans, George W. J. Fleet et al. · Organic & Biomolecular Chemistry · 2006 · 69 citations

Target Enzyme, Pharmaceutical Science, Purine Nucleoside Phosphorylases +16

Third-Generation Immucillins: Syntheses and Bioactivities of Acyclic Immucillin Inhibitors of Human Purine Nucleoside Phosphorylase

Keith Clinch, Gary B. Evans, Richard Fröhlich et al. · Journal of Medicinal Chemistry · 2009 · 69 citations · Full text

Pharmaceutical Science, Bioorganic Chemistry, Third-generation Immucillins +16