Shenghua Shi

Scaffold-based discovery of indeglitazar, a PPAR pan-active anti-diabetic agent

Dean R. Artis, Jack J. Lin, Chao Zhang et al. · Proceedings of the National Academy of Sciences · 2008 · 146 citations · Full text

Metabolic Syndrome, Medicinal Chemistry, Biochemistry +15

Optimization of Alkylidene Hydrazide Based Human Glucagon Receptor Antagonists. Discovery of the Highly Potent and Orally Available 3-Cyano-4-hydroxybenzoic Acid [1-(2,3,5,6-Tetramethylbenzyl)-1<i>H</i>-indol-4-ylmethylene]hydrazide

Peter Madsen, Anthony Ling, Michael Plewe et al. · Journal of Medicinal Chemistry · 2002 · 87 citations · Full text

An extensible and systematic force field, ESFF, for molecular modeling of organic, inorganic, and organometallic systems

Shenghua Shi, Lisa Yan, Yang Yang et al. · Journal of Computational Chemistry · 2003 · 77 citations

Torsion Energy Terms, Engineering, Force Field +14

Design of injectable agar-based composite hydrogel for multi-mode tumor therapy

Chenyao Wu, Jiulong Zhao, Fei Hu et al. · Carbohydrate Polymers · 2017 · 66 citations

Tissue Engineering, Hydrogels, Multi-mode Tumor Therapy +11

Discovery of Small Molecule Kappa Opioid Receptor Agonist and Antagonist Chemotypes through a HTS and Hit Refinement Strategy

Kevin J. Frankowski, Michael P. Hedrick, Palak Gosalia et al. · ACS Chemical Neuroscience · 2012 · 56 citations

Drug Target, High Throughput, Peptide Science +22