Palak Gosalia

Discovery of 4-oxo-6-((pyrimidin-2-ylthio)methyl)-4H-pyran-3-yl 4-nitrobenzoate (ML221) as a functional antagonist of the apelin (APJ) receptor

Patrick Maloney, Pasha M. Khan, Michael Hedrick et al. · Bioorganic & Medicinal Chemistry Letters · 2012 · 61 citations · Full text

Functional Antagonist, Biochemistry, Medicine +6

Discovery of Small Molecule Kappa Opioid Receptor Agonist and Antagonist Chemotypes through a HTS and Hit Refinement Strategy

Kevin J. Frankowski, Michael P. Hedrick, Palak Gosalia et al. · ACS Chemical Neuroscience · 2012 · 56 citations

Drug Target, High Throughput, Peptide Science +22

Discovery of ML314, a Brain Penetrant Nonpeptidic β-Arrestin Biased Agonist of the Neurotensin NTR1 Receptor

Satyamaheshwar Peddibhotla, Michael P. Hedrick, Paul Hershberger et al. · ACS Medicinal Chemistry Letters · 2013 · 48 citations · Full text

Discovery of a Plasmodium falciparum Glucose-6-phosphate Dehydrogenase 6-phosphogluconolactonase Inhibitor ( <i>R</i> , <i>Z</i> )- <i>N</i> -((1-Ethylpyrrolidin-2-yl)methyl)-2-(2-fluorobenzylidene)-3-oxo-3,4-dihydro-2 <i>H</i> -benzo[ <i>b</i> ][1,4]thiazine-6-carboxamide (ML276) That Reduces Parasite Growth in Vitro

Janina Preuss, Patrick Maloney, Satyamaheshwar Peddibhotla et al. · Journal of Medicinal Chemistry · 2012 · 37 citations · Full text

Discovery of Sulfonamidebenzamides as Selective Apoptotic CHOP Pathway Activators of the Unfolded Protein Response

Daniel P. Flaherty, Justin Miller, Danielle M. Garshott et al. · ACS Medicinal Chemistry Letters · 2014 · 20 citations