Timothy Pontz

Successful shape-Based virtual screening: The discovery of a potent inhibitor of the type I TGFβ receptor kinase (TβRI)

Juswinder Singh, Claudio Chuaqui, P. Ann Boriack‐Sjodin et al. · Bioorganic & Medicinal Chemistry Letters · 2003 · 166 citations · Full text

Virtual Screening, Tgfβ Receptor Kinase, Engineering +8

Pyrimidinone Nicotinamide Mimetics as Selective Tankyrase and Wnt Pathway Inhibitors Suitable for in Vivo Pharmacology

Jeffrey W. Johannes, Lynsie Almeida, Bernard Barlaam et al. · ACS Medicinal Chemistry Letters · 2015 · 64 citations · Full text

Pharmacotherapy, Cancer Biology, Tumor Biology +18

Potent and Selective CK2 Kinase Inhibitors with Effects on Wnt Pathway Signaling <i>in Vivo</i>

James J. Dowling, Marat Alimzhanov, Larry Bao et al. · ACS Medicinal Chemistry Letters · 2016 · 54 citations · Full text

Molecular Pharmacology, Ck2 Kinase Activity, Signal Transduction +14

Structure and Property Based Design of Pyrazolo[1,5-a]pyrimidine Inhibitors of CK2 Kinase with Activity in Vivo

James J. Dowling, Marat Alimzhanov, Larry Bao et al. · ACS Medicinal Chemistry Letters · 2013 · 53 citations · Full text

Ck2 Kinase, Medicinal Chemistry, Drug Target +14

Role of Trace Amine in the Metathesis of Imines by CpTa(NR)Cl₂

Matthew C. Burland, Timothy Pontz, Tara Y. Meyer · Organometallics · 2002 · 48 citations

Chemical Engineering, Engineering, Biochemistry +14