Concepedia

Author

Xianghan Lu

Gilead Sciences (United States)

Also Known As

Xianghan Lu

12

Publications

818

Citations

11

H-Index

23

Concepts

All Affiliations

Gilead Sciences (United States)Indian Institute of Science BangaloreUnited States Military AcademyThe University of Texas Medical Branch at GalvestonUniversity of Washington
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About

Xianghan Lu is an author at Gilead Sciences (United States) specializing in medicine, molecular biology, and viral immunity.

Top Concepts

#ConceptH-IndexPublicationsCitations

1

Medicine

3

3

246

2

Natural Sciences

1

1

20

3

Biochemistry

1

1

20

4

Immunology

1

1

214

5

Microbiology

1

1

214

Xianghan Lu

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11

Publications

812

Citations

11

H-Index

YearCitations

Design of an HA2-based <i>Escherichia coli</i> expressed influenza immunogen that protects mice from pathogenic challenge

Gayathri Bommakanti, Michael Citron, Robert W. Hepler,

Proceedings of the National Academy of Sciences

2010

214

Influenza hemagglutinin stem-fragment immunogen elicits broadly neutralizing antibodies and confers heterologous protection

Vamsee Mallajosyula, Michael Citron, Francesca Ferrara,

Proceedings of the National Academy of Sciences

2014

198

Design of Escherichia coli-Expressed Stalk Domain Immunogens of H1N1 Hemagglutinin That Protect Mice from Lethal Challenge

Gayathri Bommakanti, Xianghan Lu, Michael Citron,

Journal of Virology

2012

82

Prodrugs of a 1′-CN-4-Aza-7,9-dideazaadenosine <i>C</i>-Nucleoside Leading to the Discovery of Remdesivir (GS-5734) as a Potent Inhibitor of Respiratory Syncytial Virus with Efficacy in the African Green Monkey Model of RSV

Richard L. Mackman, Hon C. Hui, Michel Perron,

Journal of Medicinal Chemistry

2021

79

Remdesivir and GS-441524 Retain Antiviral Activity against Delta, Omicron, and Other Emergent SARS-CoV-2 Variants

Jared Pitts, Jiani Li, Jason K. Perry,

Antimicrobial Agents and Chemotherapy

2022

74

Expanded profiling of Remdesivir as a broad-spectrum antiviral and low potential for interaction with other medications in vitro

Sheli R. Radoshitzky, Patrick L. Iversen, Xianghan Lu,

Scientific Reports

2023

58

Discovery of GS-5245 (Obeldesivir), an Oral Prodrug of Nucleoside GS-441524 That Exhibits Antiviral Efficacy in SARS-CoV-2-Infected African Green Monkeys

Richard L. Mackman, Rao Kalla, Darius Babusis,

Journal of Medicinal Chemistry

2023

53

Heat Shock Protein-90 and the Catalytic Activities of the 20 S Proteasome (Multicatalytic Proteinase Complex)

Xianghan Lu, Charlene Michaud, Marian Orłowski

Archives of Biochemistry and Biophysics

2001

20

Intravenous delivery of GS-441524 is efficacious in the African green monkey model of SARS-CoV-2 infection

Jared Pitts, Darius Babusis, Meghan S. Vermillion,

Antiviral Research

2022

12

<i>In vitro</i> and <i>in vivo</i> characterization of designed immunogens derived from the CD-helix of the stem of influenza hemagglutinin

Vamsee Mallajosyula, Michael Citron, Xianghan Lu,

Proteins Structure Function and Bioinformatics

2013

11

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