Johnni Gullo-Brown

Discovery of <i>N</i>-(4-(2-Amino-3-chloropyridin-4-yloxy)-3-fluorophenyl)-4-ethoxy-1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide (BMS-777607), a Selective and Orally Efficacious Inhibitor of the Met Kinase Superfamily

Gretchen M. Schroeder, Yongmi An, Zhen‐Wei Cai et al. · Journal of Medicinal Chemistry · 2009 · 277 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +13

Discovery of (<i>R</i>)-7-Cyano-2,3,4,5-tetrahydro-1-(1<i>H</i>-imidazol-4-ylmethyl)-3- (phenylmethyl)-4-(2-thienylsulfonyl)-1<i>H</i>-1,4-benzodiazepine (BMS-214662), a Farnesyltransferase Inhibitor with Potent Preclinical Antitumor Activity

John T. Hunt, Charles Z. Ding, Roberta S. Batorsky et al. · Journal of Medicinal Chemistry · 2000 · 134 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +8

Discovery of Pyrrolopyridine−Pyridone Based Inhibitors of Met Kinase: Synthesis, X-ray Crystallographic Analysis, and Biological Activities

Kyoung Soon Kim, Liping Zhang, Robert J. Schmidt et al. · Journal of Medicinal Chemistry · 2008 · 123 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +13

Discovery of the Pyrrolo[2,1-<i>f</i>][1,2,4]triazine Nucleus as a New Kinase Inhibitor Template

John T. Hunt, Toomas Mitt, R. M. Borzilleri et al. · Journal of Medicinal Chemistry · 2004 · 92 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14

Development of Highly Potent Inhibitors of Ras Farnesyltransferase Possessing Cellular and<i>in Vivo</i>Activity

Katerina Leftheris, Toni Kline, Gregory D. Vite et al. · Journal of Medicinal Chemistry · 1996 · 88 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +13