Toomas Mitt

Discovery of Aminothiazole Inhibitors of Cyclin-Dependent Kinase 2:  Synthesis, X-ray Crystallographic Analysis, and Biological Activities

Kyoung Soon Kim, S. David Kimball, Raj N. Misra et al. · Journal of Medicinal Chemistry · 2002 · 156 citations · Full text

Combinatorial Chemistry, Drug Target, Cdk2 Protein +20

Discovery of (<i>R</i>)-7-Cyano-2,3,4,5-tetrahydro-1-(1<i>H</i>-imidazol-4-ylmethyl)-3- (phenylmethyl)-4-(2-thienylsulfonyl)-1<i>H</i>-1,4-benzodiazepine (BMS-214662), a Farnesyltransferase Inhibitor with Potent Preclinical Antitumor Activity

John T. Hunt, Charles Z. Ding, Roberta S. Batorsky et al. · Journal of Medicinal Chemistry · 2000 · 134 citations · Full text

Medicinal Chemistry, -1,4-Benzodiazepine Farnesyltransferase, Biochemistry +15

Synthesis and antiviral activity of enantiomeric forms of cyclobutyl nucleoside analogs

Gregory S. Bisacchi, Abbe Braitman, Christopher Cianci et al. · Journal of Medicinal Chemistry · 1991 · 99 citations

Bioorganic Chemistry, Engineering, Organic Chemistry +17

Discovery of the Pyrrolo[2,1-<i>f</i>][1,2,4]triazine Nucleus as a New Kinase Inhibitor Template

John T. Hunt, Toomas Mitt, R. M. Borzilleri et al. · Journal of Medicinal Chemistry · 2004 · 90 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Quinazoline-based Kinase Inhibitors +14

Total synthesis of pseudomonic acid C

Joel C. Barrish, Hsi Lin Lee, Toomas Mitt et al. · The Journal of Organic Chemistry · 1988 · 47 citations

Chemical Measurement, Chemical Analysis, Donut Icon +11