Patrick C. Fraering - Concepedia

Author

Patrick C. Fraering

École Polytechnique Fédérale de Lausanne ORCID

Also Known As

Fraering, P., Fraering, Patrick, Lorene Aeschbach, Patrick C Fraering, Patrick C. Fraering, Patrick Fraering, Patrick C. Fraering

Publications

2.8K

Citations

H-Index

Concepts

All Affiliations

École Polytechnique Fédérale de Lausanne Harvard University Brigham and Women's Hospital University of Fribourg Shanghai Jiao Tong University

About

Patrick C. Fraering is an author at École Polytechnique Fédérale de Lausanne specializing in medicine, biochemistry, and natural sciences.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	10	10	617
2	Biochemistry	10	10	782
3	Natural Sciences	9	9	747
4	Engineering	2	2	109
5	Social Sciences	2	2	97

Patrick C. Fraering

Publications

2.6K

Citations

H-Index

Page 1

	Year	Citations
Substrate-targeting γ-secretase modulators Thomas Kukar, Thomas B. Ladd, Maralyssa Bann, Nature Protein SecretionSignal TransductionProtein ExpressionBiochemistryNatural Sciences	2008	275
Purification and Characterization of the Human γ-Secretase Complex Patrick C. Fraering, Wenjuan Ye, Jean‐Marc Strub, Biochemistry	2004	227
Assembly of the γ-Secretase Complex Involves Early Formation of an Intermediate Subcomplex of Aph-1 and Nicastrin Matthew J. LaVoie, Patrick C. Fraering, Beth L. Ostaszewski, Journal of Biological Chemistry	2003	207
Electron microscopic structure of purified, active γ-secretase reveals an aqueous intramembrane chamber and two pores Vlado K. Lazarov, Patrick C. Fraering, Wenjuan Ye, Proceedings of the National Academy of Sciences Protein SecretionElectron Microscopic StructureProtein AssemblyMolecular BiologyCytoskeleton	2006	160
Detergent-Dependent Dissociation of Active γ-Secretase Reveals an Interaction between Pen-2 and PS1-NTF and Offers a Model for Subunit Organization within the Complex Patrick C. Fraering, Matthew J. LaVoie, Wenjuan Ye, Biochemistry	2003	126
The GPI Transamidase Complex of<i>Saccharomyces cerevisiae</i>Contains Gaa1p, Gpi8p, and Gpi16p Patrick C. Fraering, Isabella Imhof, Urs Meyer, Molecular Biology of the Cell	2001	113
γ-Secretase Substrate Selectivity Can Be Modulated Directly via Interaction with a Nucleotide-binding Site Patrick C. Fraering, Wenjuan Ye, Matthew J. LaVoie, Journal of Biological Chemistry	2005	99
Alzheimer’s disease mutations in APP but not γ-secretase modulators affect epsilon-cleavage-dependent AICD production Mitko Dimitrov, Jean-René Alattia, Thomas Lemmin, Nature Communications Neurodegenerative DiseasesProtein SecretionMolecular NeuroscienceAlzheimer's DiseaseMedicine	2013	91
Zinc and Copper Differentially Modulate Amyloid Precursor Protein Processing by γ-Secretase and Amyloid-β Peptide Production Hermeto Gerber, Fang Wu, Mitko Dimitrov, Journal of Biological Chemistry BiochemistryNatural SciencesMetalloproteinBioactive MetalMolecular Biology	2017	82
A Compressible Scaffold for Minimally Invasive Delivery of Large Intact Neuronal Networks Amélie Béduer, Thomas Braschler, Oliver Peric, Advanced Healthcare Materials	2014	81

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