Mark A. Zottola

Mechanism of slow-binding inhibition of human leukocyte elastase by trifluoromethyl ketones

Ross L. Stein, Anne M. Strimpler, Phillip D. Edwards et al. · Biochemistry · 1987 · 102 citations

Human Leukocyte Elastase, Hemiketal Intermediate, Chemical Biology +19

A practical, efficient large-scale synthesis of 1,6-anhydrohexopyranoses

Mark A. Zottola, Ricardo Alonso, Gregory D. Vite et al. · The Journal of Organic Chemistry · 1989 · 69 citations

Biosynthesis, Bioorganic Chemistry, Molecular Sciences +15

Carbohydrates to carbocycles: synthesis of the densely functionalized carbocyclic core of tetrodotoxin by radical cyclization of an anhydro sugar precursor

Ricardo Alonso, Christopher S. Burgey, B. Venkateswara Rao et al. · Journal of the American Chemical Society · 1993 · 57 citations

Bioorganic Chemistry, Engineering, Altmetric Attention Score +16

Discovery and Biological Activity of Orally Active Peptidyl Trifluoromethyl Ketone Inhibitors of Human Neutrophil Elastase

Philip D. Edwards, Donald W. Andisik, Craig A. Bryant et al. · Journal of Medicinal Chemistry · 1997 · 51 citations · Full text

Peptidyl .alpha.-ketoheterocyclic inhibitors of human neutrophil elastase. 3. In vitro and in vivo potency of a series of peptidyl .alpha.-ketobenzoxazoles

Philip D. Edwards, Mark A. Zottola, Matthew W. Davis et al. · Journal of Medicinal Chemistry · 1995 · 50 citations · Full text