David Hangauer

An interactive computer graphics study of thermolysin-catalyzed peptide cleavage and inhibition by N-carboxymethyl dipeptides

David Hangauer, A.F. Monzingo, Brian W. Matthews · Biochemistry · 1984 · 249 citations

Non-additivity of Functional Group Contributions in Protein–Ligand Binding: A Comprehensive Study by Crystallography and Isothermal Titration Calorimetry

Bernhard Baum, Laveena Muley, Michael Smolinski et al. · Journal of Molecular Biology · 2010 · 160 citations

Protein Chemistry, Engineering, Biochemistry +12

Dissecting the Hydrophobic Effect on the Molecular Level: The Role of Water, Enthalpy, and Entropy in Ligand Binding to Thermolysin

Nader N. Nasief, Michael Betz, A. Heine et al. · Angewandte Chemie International Edition · 2013 · 145 citations

Protein Chemistry, Proteinlipid Interaction, Protein Assembly +14

More than a Simple Lipophilic Contact: A Detailed Thermodynamic Analysis of Nonbasic Residues in the S1 Pocket of Thrombin

Bernhard Baum, Menshawy Mohamed, Mohamed F. Zayed et al. · Journal of Molecular Biology · 2009 · 130 citations

Protein Chemistry, Proteinlipid Interaction, Protein Assembly +10

Design of a selective insulin receptor tyrosine kinase inhibitor and its effect on glucose uptake and metabolism in intact cells

Richard Saperstein, Pasquale P. Vicario, H.V. Strout et al. · Biochemistry · 1989 · 108 citations

Intact Cells, Insulin Receptor, Glucose Uptake +20