Concepedia

Nader N. Nasief

NN

Statistics

Publications

5

Citations

289

H-Index

5

Active since

2012

Affiliations

University at Buffalo, State University of New York(Current)

Nader N. Nasief is an author at University at Buffalo, State University of New York specializing in natural sciences, biochemistry, and chemistry.

Top concepts

Publications per year

2012–2021

5

Publications

5

Dissecting the Hydrophobic Effect on the Molecular Level: The Role of Water, Enthalpy, and Entropy in Ligand Binding to Thermolysin

Nader N. Nasief, Michael Betz, A. Heine et al. · Angewandte Chemie International Edition · 2013 · 145 citations

, , +14

Discovery and Characterization of Potent Dual P-Glycoprotein and CYP3A4 Inhibitors: Design, Synthesis, Cryo-EM Analysis, and Biological Evaluations

Sameer Urgaonkar, Kamil Nosol, Ahmed M. Said et al. · Journal of Medicinal Chemistry · 2021 · 67 citations · Full text

Water Mediated Ligand Functional Group Cooperativity: The Contribution of a Methyl Group to Binding Affinity is Enhanced by a COO<sup>–</sup> Group Through Changes in the Structure and Thermodynamics of the Hydration Waters of Ligand–Thermolysin Complexes

Nader N. Nasief, Hongwei Tan, Jing Kong et al. · Journal of Medicinal Chemistry · 2012 · 38 citations · Full text

, , +14

Influence of Neighboring Groups on the Thermodynamics of Hydrophobic Binding: An Added Complex Facet to the Hydrophobic Effect

Nader N. Nasief, David Hangauer · Journal of Medicinal Chemistry · 2014 · 24 citations

Additivity or cooperativity: Which model can predict the influence of simultaneous incorporation of two or more functionalities in a ligand molecule?

Nader N. Nasief, David Hangauer · European Journal of Medicinal Chemistry · 2014 · 15 citations · Full text

, , +8

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