Bernhard Baum

Non-additivity of Functional Group Contributions in Protein–Ligand Binding: A Comprehensive Study by Crystallography and Isothermal Titration Calorimetry

Bernhard Baum, Laveena Muley, Michael Smolinski et al. · Journal of Molecular Biology · 2010 · 160 citations

Protein Chemistry, Engineering, Biochemistry +12

More than a Simple Lipophilic Contact: A Detailed Thermodynamic Analysis of Nonbasic Residues in the S1 Pocket of Thrombin

Bernhard Baum, Menshawy Mohamed, Mohamed F. Zayed et al. · Journal of Molecular Biology · 2009 · 130 citations

Protein Chemistry, Proteinlipid Interaction, Protein Assembly +10

Enhancement of Hydrophobic Interactions and Hydrogen Bond Strength by Cooperativity: Synthesis, Modeling, and Molecular Dynamics Simulations of a Congeneric Series of Thrombin Inhibitors

Laveena Muley, Bernhard Baum, Michael Smolinski et al. · Journal of Medicinal Chemistry · 2010 · 89 citations · Full text

Drug Target, Thrombin Inhibitors, Engineering +17

Congeneric but Still Distinct: How Closely Related Trypsin Ligands Exhibit Different Thermodynamic and Structural Properties

Tobias Brandt, Nicole Holzmann, Laveena Muley et al. · Journal of Molecular Biology · 2010 · 54 citations · Full text

Protein Chemistry, Structural Properties, Biochemistry +5

Think Twice: Understanding the High Potency of Bis(phenyl)methane Inhibitors of Thrombin

Bernhard Baum, Laveena Muley, A. Heine et al. · Journal of Molecular Biology · 2009 · 54 citations · Full text

Thrombosis, Medicinal Chemistry, Biochemistry +13