Anti- and pro-oxidant activity of rutin and quercetin derivatives

Marc Kessler, G. Ubeaud, Louis Jung

Journal of Pharmacy and Pharmacology

Structural FeaturesMedicinal ChemistryPolyphenolicsBiochemistryPosition 7 +11

The Use of Human Hepatocytes to Select Compounds Based on Their Expected Hepatic Extraction Ratios in Humans

T. Lave, Sylvie Dupin, Christophe Schmitt, +5

Pharmaceutical Research

Quercetin and naringenin transport across human intestinal Caco-2 cells

Meriem Nait Chabane, Abraham Al Ahmad, Jean Peluso, +2

Journal of Pharmacy and Pharmacology

Gastrointestinal PharmacologyGastroenterologyNaringenin TransportDigestive TractCellular Physiology +14

Bosentan, a new endothelin receptor antagonist: prediction of the systemic plasma clearance in man from combined in vivo and in vitro data

G. Ubeaud, Christophe Schmitt, D Jaeck, +2

Xenobiotica

Interspecies Scaling of Bosentan, A New Endothelin Receptor Antagonist and Integration of in Vitro Data into Allometric Scaling

Thierry Lavé, Philippe Coassolo, G. Ubeaud, +5

Pharmaceutical Research

In vitro inhibition of simvastatin metabolism in rat and human liver by naringenin

G. Ubeaud, J. Hagenbach, S. Vandenschrieck, +2

Life Sciences

Molecular PharmacologyVitro InhibitionBiochemistryMedicineLiver Physiology +12

A new extrapolation method from animals to man: Application to a metabolized compound, mofarotene

Thierry Lavé, Anne Schmitt‐Hoffmann, Philippe Coassolo, +5

Life Sciences

Medicinal ChemistryBiochemistryMedicineNatural SciencesBioanalysis +10

Free radical scavenging and skin penetration of troxerutin and vitamin derivatives

Marc Kessler, G. Ubeaud, Tatjana Walter, +2

Journal of Dermatological Treatment

In vitro inhibition of simvastatin metabolism, a HMG-CoA reductase inhibitor in human and rat liver by bergamottin, a component of grapefruit juice

Nathalie Le Goff-Klein, Jean-Claude Koffel, Louis Jung, +1

European Journal of Pharmaceutical Sciences

PolyphenolicsBiochemistryMedicineLiver PhysiologyPhysiology +8

Estimation of flavin-containing monooxygenase activity in intact hepatocyte monolayers of rat, hamster, rabbit, dog and human by using N-oxidation of benzydamine

G. Ubeaud, Claus-Ditter Schiller, Fabrice Hurbin, +2

European Journal of Pharmaceutical Sciences

BiochemistryMedicineLiver PhysiologyBioanalysisFlavin-containing Monooxygenase Activity +10