Concepedia

T. Lave

TL

Statistics

Publications

3

Citations

327

H-Index

3

Active since

1996

Affiliations

Roche (Switzerland)(Current)

T. Lave is an author at Roche (Switzerland) specializing in metabolic signaling, animal physiology, and metabolomics.

Top concepts

Publications per year

1996–1997

3

Publications

3

Integration of in Vitro Data into Allometric Scaling to Predict Hepatic Metabolic Clearance in Man: Application to 10 Extensively Metabolized Drugs

T. Lave, Sylvie Dupin, Christophe Schmitt et al. · Journal of Pharmaceutical Sciences · 1997 · 179 citations

The Use of Human Hepatocytes to Select Compounds Based on Their Expected Hepatic Extraction Ratios in Humans

T. Lave, Sylvie Dupin, Christophe Schmitt et al. · Pharmaceutical Research · 1997 · 105 citations

Interspecies scaling of tolcapone, a new inhibitor of catechol-<i>O</i>-methyltransferase (COMT). Use of<i>in vitro</i>data from hepatocytes to predict metabolic clearance in animals and humans

T. Lave, Sylvie Dupin, Monique Schmitt et al. · Xenobiotica · 1996 · 43 citations

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