Fecal Serine Protease Profiling in Inflammatory Bowel Diseases

Amin Jablaoui, Aïcha Kriaa, Héla Mkaouar, +9

Frontiers in Cellular and Infection Microbiology

Protease InhibitorsInflammationMucosal ImmunologyBiochemistryFecal Protease Activities +12

Introduction of non-natural amino acid residues into the substrate-specific P1 position of trypsin inhibitor SFTI-1 yields potent chymotrypsin and cathepsin G inhibitors

Anna Łęgowska, Dawid Dębowski, Adam Lesner, +2

Bioorganic & Medicinal Chemistry

Protein FunctionBiochemistryG Protein-coupled ReceptorMedicineCathepsin G Inhibitors +6

New Selective Peptidyl Di(chlorophenyl) Phosphonate Esters for Visualizing and Blocking Neutrophil Proteinase 3 in Human Diseases

Carla Guarino, Monika Łęgowska, Christophe Epinette, +13

Journal of Biological Chemistry

Bioorganic ChemistryChemical BiologyInflammatory Lung SecretionsMedicinal ChemistryHuman Diseases +14

Biochemical and Structural Characterization of SplD Protease from Staphylococcus aureus

Michal Zdzalik, Magdalena Kalińska, Magdalena Wysocka, +15

PLoS ONE

Protein AssemblyBiochemistryMedicineNatural SciencesPeptide Library +7

Structure-based design and in vivo anti-arthritic activity evaluation of a potent dipeptidyl cyclopropyl nitrile inhibitor of cathepsin C

Brice Korkmaz, Adam Lesner, Magdalena Wysocka, +7

Biochemical Pharmacology

Medicinal ChemistryPharmaceutical ScienceAnti-inflammatoryBiochemistryMedicine +9

New chromogenic substrates of human neutrophil cathepsin G containing non-natural aromatic amino acid residues in position P1 selected by combinatorial chemistry methods

Magdalena Wysocka, Anna Łęgowska, Elżbieta Bulak, +4

Molecular Diversity

Protein ChemistryCombinatorial Chemistry MethodsBiochemistryPosition P1Natural Sciences +6

Design of selective substrates of proteinase 3 using combinatorial chemistry methods

Magdalena Wysocka, Adam Lesner, Katarzyna Guzow, +4

Analytical Biochemistry

Selective SubstratesCombinatorial Chemistry MethodsBiochemistryEngineeringNatural Sciences +10

Substrate specificity and inhibitory study of human airway trypsin-like protease

Magdalena Wysocka, Bożena Spichalska, Adam Lesner, +4

Bioorganic & Medicinal Chemistry

Protease InhibitorsProtein FunctionAllergyBiochemistryMedicine +4

Three Wavelength Substrate System of Neutrophil Serine Proteinases

Magdalena Wysocka, Adam Lesner, Natalia Gruba, +5

Analytical Chemistry

Protein ChemistryProteinlipid InteractionProtein FunctionFluorescence DonorsBiochemistry +13

Meta-analysis informed machine learning: Supporting cytokine storm detection during CAR-T cell Therapy

Alex Bogatu, Magdalena Wysocka, Oskar Wysocki, +7

Journal of Biomedical Informatics