Fiona Brown

Cell Penetrant Inhibitors of the KDM4 and KDM5 Families of Histone Lysine Demethylases. 2. Pyrido[3,4-<i>d</i>]pyrimidin-4(3<i>H</i>)-one Derivatives

Susan M. Westaway, Alex Preston, Michael D. Barker et al. · Journal of Medicinal Chemistry · 2016 · 67 citations · Full text

Drug Target, Molecular Biology, Kdm5 Families +18

Cell Penetrant Inhibitors of the KDM4 and KDM5 Families of Histone Lysine Demethylases. 1. 3-Amino-4-pyridine Carboxylate Derivatives

Susan M. Westaway, Alex Preston, Michael D. Barker et al. · Journal of Medicinal Chemistry · 2016 · 59 citations · Full text

Mechanistic Kdm4c Cell, Molecular Biology, Kdm5 Families +17

The discovery of a series of N-substituted 3-(4-piperidinyl)-1,3-benzoxazolinones and oxindoles as highly brain penetrant, selective muscarinic M1 agonists

Dale J. Johnson, Ian T. Forbes, Steve P. Watson et al. · Bioorganic & Medicinal Chemistry Letters · 2010 · 25 citations · Full text

Brain Penetrant, Medicine, Mechanism Of Action +6

The identification of novel orally active mGluR5 antagonist GSK2210875

Maria Pilla, Michela Andreoli, Michela Tessari et al. · Bioorganic & Medicinal Chemistry Letters · 2010 · 24 citations · Full text

Molecular Pharmacology, Active Mglur5, G Protein-coupled Receptor +7

Configuration of a High-Content Imaging Platform for Hit Identification and Pharmacological Assessment of JMJD3 Demethylase Enzyme Inhibitors

Alpa Mulji, Carl Haslam, Fiona Brown et al. · SLAS DISCOVERY · 2012 · 20 citations · Full text