Huangshu Lei - Concepedia

Author

Huangshu Lei

Also Known As

H. Lei, Hao-Xue Lei, Hao‐Xue Lei, Huang-Shu Lei, Huangshu (John) Lei, Huangshu J. Lei, Huangshu John Lei, Huangshu Lei, Huiling Lei

Publications

631

Citations

H-Index

Concepts

All Affiliations

Brock University Research Triangle Park Foundation GlaxoSmithKline (United States)Pfizer (United States)University of Birmingham

About

Huangshu Lei is an author at Brock University specializing in medicine, pharmacology, and natural sciences.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	11	11	494
2	Natural Sciences	9	9	441
3	Biochemistry	8	8	354
4	Engineering	2	2	28
5	Biomolecular Engineering	1	1	19

Huangshu Lei

Publications

597

Citations

H-Index

Page 1

	Year	Citations
Identification of NVP-TNKS656: The Use of Structure–Efficiency Relationships To Generate a Highly Potent, Selective, and Orally Active Tankyrase Inhibitor Michael D. Shultz, Atwood K. Cheung, C.A. Kirby, Journal of Medicinal Chemistry Drug TargetSelective Tankyrase InhibitorsPharmacotherapyChemical BiologyPharmaceutical Chemistry	2013	122
1-Amino-4-benzylphthalazines as Orally Bioavailable Smoothened Antagonists with Antitumor Activity Karen Miller‐Moslin, Stefan Peukert, Rishi K. Jain, Journal of Medicinal Chemistry Pharmaceutical ScienceAntitumor ActivityPharmacotherapyPharmaceutical ChemistryTumor Biology	2009	106
Optimization of 4,6-bis-anilino-1H-pyrrolo[2,3-d]pyrimidine IGF-1R tyrosine kinase inhibitors towards JNK selectivity Stanley D. Chamberlain, Anikó M. Redman, Joseph W. Wilson, Bioorganic & Medicinal Chemistry Letters Medicinal ChemistryBiochemistryNatural SciencesMedicineReceptor Tyrosine Kinase	2008	57
Design, synthesis, and biological evaluation of dihydroartemisinin–fluoroquinolone conjugates as a novel type of potential antitubercular agents Fu-Wei Zhou, Huangshu Lei, Fan Li, Bioorganic & Medicinal Chemistry Letters Bioorganic ChemistryNovel TypeBiochemistryDihydroartemisinin–fluoroquinolone ConjugatesMedicine	2014	51
Synthesis of Phytyl- and Chroman-Derivatized Photoaffinity Labels Based on α-Tocopherol Huangshu Lei, Jeffrey Atkinson The Journal of Organic Chemistry	2000	37
The design and synthesis of human branched-chain amino acid aminotransferase inhibitors for treatment of neurodegenerative diseases Lain‐Yen Hu, Peter A. Boxer, Suzanne R. Kesten, Bioorganic & Medicinal Chemistry Letters Neurodegenerative DiseasesBiochemistryMedicineRational Drug DesignPeptide Synthesis	2005	32
Discovery of 4,6-bis-anilino-1H-pyrrolo[2,3-d]pyrimidines: Potent inhibitors of the IGF-1R receptor tyrosine kinase Stanley D. Chamberlain, Joseph W. Wilson, Felix Deanda, Bioorganic & Medicinal Chemistry Letters BiochemistryMedicineNatural SciencesReceptor Tyrosine KinaseRational Drug Design	2008	30
Discovery of 3,5-disubstituted-1H-pyrrolo[2,3-b]pyridines as potent inhibitors of the insulin-like growth factor-1 receptor (IGF-1R) tyrosine kinase Samarjit Patnaik, Kirk L. Stevens, Roseanne Gerding, Bioorganic & Medicinal Chemistry Letters Medicinal ChemistryBiochemistryMedicineTyrosine KinaseNatural Sciences	2009	26
Cobdock: an accurate and practical machine learning-based consensus blind docking method Sadettin Y. Ugurlu, David W. McDonald, Huangshu Lei, Journal of Cheminformatics	2024	26
Expression and Refolding of Recombinant Human α-Tocopherol Transfer Protein Capable of Specific α-Tocopherol Binding Candace Panagabko, Samantha Morley, Steve Neely, Protein Expression and Purification XenotransplantationBiochemistryNatural SciencesMolecular BiologySpecific α-Tocopherol Binding	2002	20

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