Benjamin I. Leach

WNT Signaling and Colorectal Cancer

Emma M. Schatoff, Benjamin I. Leach, Lukas E. Dow · Current Colorectal Cancer Reports · 2017 · 308 citations · Full text

Tumor Biology, Oncology, Medicine +6

Transplantation of engineered organoids enables rapid generation of metastatic mouse models of colorectal cancer

Kevin P. O’Rourke, Evangelia Loizou, Geulah Livshits et al. · Nature Biotechnology · 2017 · 233 citations · Full text

Xenotransplantation, Medicine, Colorectal Cancer +9

Leukemia Fusion Target AF9 Is an Intrinsically Disordered Transcriptional Regulator that Recruits Multiple Partners via Coupled Folding and Binding

Benjamin I. Leach, Aravinda Kuntimaddi, Charles Schmidt et al. · Structure · 2012 · 111 citations · Full text

Chromatin, Transcriptional Regulation, Chromatin Remodeling +12

Engineering of the methylmalonyl-CoA metabolite node of Saccharopolyspora erythraea for increased erythromycin production

Andrew R. Reeves, Igor Brikun, William H. Cernota et al. · Metabolic Engineering · 2007 · 100 citations · Full text

Biosynthesis, Engineering, Biotransformation +12

Distinct Colorectal Cancer–Associated APC Mutations Dictate Response to Tankyrase Inhibition

Emma M. Schatoff, Sukanya Goswami, María Paz Zafra et al. · Cancer Discovery · 2019 · 88 citations · Full text