Johanna H.K. Kauppila

MitoTALEN reduces mutant mtDNA load and restores tRNAAla levels in a mouse model of heteroplasmic mtDNA mutation

Sandra R. Bacman, Johanna H.K. Kauppila, Cláudia V. Pereira et al. · Nature Medicine · 2018 · 276 citations

Biology, Genome Instability, Mitochondrial Function +9

Mitochondrial fusion is required for regulation of mitochondrial DNA replication

Eduardo Silva Ramos, Elisa Motori, Christian Brüser et al. · PLoS Genetics · 2019 · 171 citations · Full text

Mitophagy, Genetics, Molecular Biology +18

A Phenotype-Driven Approach to Generate Mouse Models with Pathogenic mtDNA Mutations Causing Mitochondrial Disease

Johanna H.K. Kauppila, Holly L. Baines, Ana Bratić et al. · Cell Reports · 2016 · 140 citations · Full text

A salvage pathway maintains highly functional respiratory complex I

Karolina Szczepanowska, Katharina Senft, Juliana Heidler et al. · Nature Communications · 2020 · 114 citations · Full text

Base-excision repair deficiency alone or combined with increased oxidative stress does not increase mtDNA point mutations in mice

Johanna H.K. Kauppila, Nina A. Bonekamp, Arnaud Mourier et al. · Nucleic Acids Research · 2018 · 72 citations · Full text

Dna Damage, Genetics, Molecular Biology +19