Sandra R. Bacman

Specific elimination of mutant mitochondrial genomes in patient-derived cells by mitoTALENs

Sandra R. Bacman, Siôn L. Williams, Milena Pinto et al. · Nature Medicine · 2013 · 436 citations

Life Sciences, Genetics, Molecular Genetics +16

Selective Elimination of Mitochondrial Mutations in the Germline by Genome Editing

Pradeep Reddy, Alejandro Ocampo, Keiichiro Suzuki et al. · Cell · 2015 · 286 citations · Full text

Life Sciences, Genetics, Molecular Genetics +11

MitoTALEN reduces mutant mtDNA load and restores tRNAAla levels in a mouse model of heteroplasmic mtDNA mutation

Sandra R. Bacman, Johanna H.K. Kauppila, Cláudia V. Pereira et al. · Nature Medicine · 2018 · 283 citations

Life Sciences, Genetics, Molecular Biology +14

MitoTALEN: A General Approach to Reduce Mutant mtDNA Loads and Restore Oxidative Phosphorylation Function in Mitochondrial Diseases

Masami Hashimoto, Sandra R. Bacman, Susana Peralta et al. · Molecular Therapy · 2015 · 198 citations · Full text

Life Sciences, Genetics, Molecular Biology +17

Cytochrome<i>c</i>Association with the Inner Mitochondrial Membrane Is Impaired in the CNS of G93A-SOD1 Mice

Ilias G. Kirkinezos, Sandra R. Bacman, Dayami Hernandez et al. · Journal of Neuroscience · 2005 · 198 citations · Full text

Life Sciences, Neurology, Neuroscience +17