Barbara J. Brandhuber

RAF inhibitors prime wild-type RAF to activate the MAPK pathway and enhance growth

Georgia Hatzivassiliou, Kyung Song, Ivana Yen et al. · Nature · 2010 · 1.6K citations · Full text

Signaling Pathway, Receptor Tyrosine Kinase, Mapk Pathway +8

Biological Characterization of ARRY-142886 (AZD6244), a Potent, Highly Selective Mitogen-Activated Protein Kinase Kinase 1/2 Inhibitor

Tammie C. Yeh, Vivienne Marsh, Bryan A. Bernat et al. · Clinical Cancer Research · 2007 · 575 citations · Full text

Interleukin-1 (IL-1) receptor antagonist binds to the 80-kDa IL-1 receptor but does not initiate IL-1 signal transduction

David J. Dripps, Barbara J. Brandhuber, Richard Thompson et al. · Journal of Biological Chemistry · 1991 · 454 citations · Full text

Selective RET kinase inhibition for patients with RET-altered cancers

Vivek Subbiah, Vamsidhar Velcheti, Brian B. Tuch et al. · Annals of Oncology · 2018 · 422 citations · Full text

A Next-Generation TRK Kinase Inhibitor Overcomes Acquired Resistance to Prior TRK Kinase Inhibition in Patients with TRK Fusion–Positive Solid Tumors

Alexander Drilon, Ramamoorthy Nagasubramanian, James F. Blake et al. · Cancer Discovery · 2017 · 419 citations · Full text