IRF5 promotes inflammatory macrophage polarization and TH1-TH17 responses

Thomas Krausgruber, Katrina Blazek, Tim Smallie, +6

Nature Immunology

Porphyromonas gingivalis Facilitates the Development and Progression of Destructive Arthritis through Its Unique Bacterial Peptidylarginine Deiminase (PAD)

Katarzyna Maresz, Annelie Hellvard, Aneta Sroka, +14

PLoS Pathogens

ImmunologyPathologyOral MicrobiologyInflammationRheumatoid Disorder +16

Blockade of tumor necrosis factor in collagen-induced arthritis reveals a novel immunoregulatory pathway for Th1 and Th17 cells

Clare A. Notley, Julia J. Inglis, Saba Alzabin, +3

The Journal of Experimental Medicine

Incomplete response of inflammatory arthritis to TNFα blockade is associated with the Th17 pathway

Saba Alzabin, Sonya Abraham, Taher E. Taher, +9

Annals of the Rheumatic Diseases

Immunization with Porphyromonas gingivalis enolase induces autoimmunity to mammalian α-enolase and arthritis in DR4-IE-transgenic mice

A. J. Kinloch, Saba Alzabin, William Brintnell, +6

Arthritis & Rheumatism

Reporter gene assay for the quantification of the activity and neutralizing antibody response to TNFα antagonists

Christophe Lallemand, Nadia Kavrochorianou, Casper Steenholdt, +9

Journal of Immunological Methods

Tnfα AntagonistsAllergyReporter Gene AssayImmunologyImmune Surveillance +4

Hematopoietic Progenitor Kinase 1 Is a Negative Regulator of Dendritic Cell Activation

Saba Alzabin, Nina Bhardwaj, Friedemann Kiefer, +2

The Journal of Immunology

Hematopoietic progenitor kinase 1 is a critical component of prostaglandin E2-mediated suppression of the anti-tumor immune response

Saba Alzabin, Saiju Pyarajan, Herman Yee, +4

Cancer Immunology Immunotherapy

IL-17 induces hyperalgesia via TNF-dependent neutrophil infiltration

Kay McNamee, Saba Alzabin, Jane P. Hughes, +4

Pain

Investigation of the role of endosomal Toll-like receptors in murine collagen-induced arthritis reveals a potential role for TLR7 in disease maintenance

Saba Alzabin, Philip Kong, Mino Medghalchi, +3

Arthritis Research & Therapy