Jacek Mokrosiński

MC4R agonism promotes durable weight loss in patients with leptin receptor deficiency

Karine Clément, Heike Biebermann, I. Sadaf Farooqi et al. · Nature Medicine · 2018 · 294 citations

Obesity, Metabolic Syndrome, Nutrition +11

Evaluation of a melanocortin-4 receptor (MC4R) agonist (Setmelanotide) in MC4R deficiency

Tinh‐Hai Collet, B. Dubern, Jacek Mokrosiński et al. · Molecular Metabolism · 2017 · 286 citations · Full text

Human Gain-of-Function MC4R Variants Show Signaling Bias and Protect against Obesity

Luca A. Lotta, Jacek Mokrosiński, Edson Mendes de Oliveira et al. · Cell · 2019 · 273 citations · Full text

Palmitic Acid Hydroxystearic Acids Activate GPR40, Which Is Involved in Their Beneficial Effects on Glucose Homeostasis

Ismail Syed, Jennifer Lee, Pedro M. Moraes‐Vieira et al. · Cell Metabolism · 2018 · 185 citations · Full text

Metabolic Syndrome, Biochemistry, Medicine +9

Loss-of-function mutations in the melanocortin 4 receptor in a UK birth cohort

Kaitlin H. Wade, Brian Lam, Audrey Melvin et al. · Nature Medicine · 2021 · 121 citations · Full text

Developmental Biology, Melanocortin 4, Genetic Disorder +9