Concepedia

MC4R agonism promotes durable weight loss in patients with leptin receptor deficiency

Karine Clément, Heike Biebermann, I. Sadaf Farooqi, Lex Van der Ploeg, Barbara Wolters, Christine Poitou, Lia Puder, Fred T. Fiedorek, Keith Gottesdiener, Gunnar Kleinau,

Nature Medicine · 2018 · 310 citations · 20 references

DOI

Concepts

References

20

Crystal structure of the β2 adrenergic receptor–Gs protein complex

Søren G. F. Rasmussen, Brian T. DeVree, Yaozhong Zou et al. · Nature · 2011 · 3.1K citations · Full text

, , +12

A mutation in the human leptin receptor gene causes obesity and pituitary dysfunction

Karine Clément, Christian Vaisse, Najiba Lahlou et al. · Nature · 1998 · 2.4K citations

, , +13

Effects of Recombinant Leptin Therapy in a Child with Congenital Leptin Deficiency

I. Sadaf Farooqi, Susan A. Jebb, Gill Langmack et al. · New England Journal of Medicine · 1999 · 2K citations · Full text

, , +17

Antagonism of Central Melanocortin Receptors in Vitro and in Vivo by Agouti-Related Protein

Michael M. Ollmann, Brent D. Wilson, Yingkui Yang et al. · Science · 1997 · 1.9K citations

, , +14

Molecular cloning, expression, and gene localization of a fourth melanocortin receptor

Ira Gantz, Hiroto Miwa, Y Konda et al. · Journal of Biological Chemistry · 1993 · 852 citations · Full text

, , +16