Yuching Chen

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Publications

Citations

3.2K

H-Index

Active since

2001

Affiliations

Wellspring Biosciences (United States)(Current)

University of Washington

Kura Oncology (United States)

Yuching Chen is an author at Wellspring Biosciences (United States) specializing in pathogen virulence factors, medicinal chemistry, and kras g12c inhibition.

Publications per year

2001–2018

Publications

Targeting KRAS Mutant Cancers with a Covalent G12C-Specific Inhibitor

Matthew R. Janes, Jingchuan Zhang, Lian‐Sheng Li et al. · Cell · 2018 · 1.2K citations · Full text

Pharmacy, Medicinal Chemistry, Oncology +12

The Genome of the Natural Genetic Engineer <i>Agrobacterium tumefaciens</i> C58

Derek W. Wood, João Carlos Setúbal, Rajinder Kaul et al. · Science · 2001 · 783 citations

Life Sciences, Evolutionary Biology, Genetics +17

Selective Inhibition of Oncogenic KRAS Output with Small Molecules Targeting the Inactive State

Matthew P. Patricelli, Matthew R. Janes, Lian‐Sheng Li et al. · Cancer Discovery · 2016 · 754 citations · Full text

Medicine, Medicinal Chemistry, Oncology +17

AZD1208, a potent and selective pan-Pim kinase inhibitor, demonstrates efficacy in preclinical models of acute myeloid leukemia

Erika Krasnickas Keeton, Kristen McEachern, Keith Dillman et al. · Blood · 2013 · 247 citations

Medicine, Medicinal Chemistry, Pharmacology +11

The reactivity-driven biochemical mechanism of covalent KRASG12C inhibitors

Rasmus Hansen, Ulf Peters, Anjali Babbar et al. · Nature Structural & Molecular Biology · 2018 · 149 citations

Pharmacy, Biochemistry, Chemistry +14

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