Concepedia

Y. Joy Yu Zuchero

YJ

10

Publications

1.4K

Citations

10

H-Index

2015

Active since

Affiliations

Denali Therapeutics (United States)(Current)

Biogen (United States)

University of Minnesota

Y. Joy Yu Zuchero is an author at Denali Therapeutics (United States) specializing in neuroinflammation, neuroimmunology, and immunotherapy.

ORCID

Top concepts

Publications per year

2015–2025

10

Publications

10

Brain delivery of therapeutic proteins using an Fc fragment blood-brain barrier transport vehicle in mice and monkeys

Mihalis S. Kariolis, Robert C. Wells, Jennifer A. Getz et al. · Science Translational Medicine · 2020 · 331 citations

Effector-attenuating Substitutions That Maintain Antibody Stability and Reduce Toxicity in Mice

Megan Lo, Hok Seon Kim, Raymond K. Tong et al. · Journal of Biological Chemistry · 2017 · 315 citations · Full text

Discovery of Novel Blood-Brain Barrier Targets to Enhance Brain Uptake of Therapeutic Antibodies

Y. Joy Yu Zuchero, Xiaocheng Chen, Nga Bien‐Ly et al. · Neuron · 2015 · 284 citations · Full text

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A TREM2-activating antibody with a blood–brain barrier transport vehicle enhances microglial metabolism in Alzheimer’s disease models

Bettina van Lengerich, Lihong Zhan, Dan Xia et al. · Nature Neuroscience · 2023 · 213 citations · Full text

Targeting the transferrin receptor to transport antisense oligonucleotides across the mammalian blood-brain barrier

Scarlett J. Barker, Mai B. Thayer, Chaeyoung Kim et al. · Science Translational Medicine · 2024 · 93 citations

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