Concepedia
Statistics
Publications
30
Citations
2K
H-Index
24
Active since
1977
Affiliations
Roche (Switzerland)(Current)
Actelion (Switzerland)
Laboratoire de Chimie Organique
Novartis (Switzerland)
Morpho (United States)
Christian Hubschwerlen is an author at Roche (Switzerland) specializing in drug discovery, medicinal chemistry, and pharmacology.
Publications per year
1977–2024
Refined crystal structure of β-lactamase from Citrobacter freundiiindicates a mechanism for β-lactam hydrolysis
Christian Oefner, A. D’Arcy, J. J. Daly et al. · Nature · 1990 · 299 citations
Life Sciences, Biochemistry, Microbiology +9
A Convenient Synthesis of L-(<i>S</i>)-Glyceraldehyde Acetonide from L-Ascorbic Acid
Christian Hubschwerlen · Synthesis · 1986 · 153 citations
Natural Sciences, Biochemistry, Chemistry +3
Peptide Deformylase as an Antibacterial Drug Target: Target Validation and Resistance Development
Christian Apfel, Hans H. Locher, Stefan Evers et al. · Antimicrobial Agents and Chemotherapy · 2001 · 126 citations · Full text
Life Sciences, Microbiology, Molecular Biology +17
Hydroxamic Acid Derivatives as Potent Peptide Deformylase Inhibitors and Antibacterial Agents
Christian Apfel, David W. Banner, Daniel Bur et al. · Journal of Medicinal Chemistry · 2000 · 112 citations · Full text
Life Sciences, Medicinal Chemistry, Pharmacology +17
Discovery and Optimization of Isoquinoline Ethyl Ureas as Antibacterial Agents
Philippe Panchaud, Thierry Bruyère, A.-C. Blumstein et al. · Journal of Medicinal Chemistry · 2017 · 105 citations · Full text
Pharmacy, Medicinal Chemistry, Pharmacology +17
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