Hans H. Locher - Concepedia

Author

Hans H. Locher

Also Known As

H H Locher, H. H. Locher, H.H. Locher, Hans H Locher, Hans H. Locher, Hans Locher, Locher, H., Locher, Hans, Locher, Hans Heinrich

Publications

2.1K

Citations

H-Index

Concepts

All Affiliations

Actelion (Switzerland)École Polytechnique Fédérale de Lausanne Roche (Switzerland)ETH Zurich University of Zurich

About

Hans H. Locher is an author at Actelion (Switzerland) specializing in medicine, microbiology, and natural sciences.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	17	18	1.4K
2	Natural Sciences	13	13	887
3	Biochemistry	13	13	943
4	Engineering	5	5	249
5	Health Sciences	3	3	142

Hans H. Locher

Publications

Citations

H-Index

Page 1

	Year	Citations
Chimeric peptidomimetic antibiotics against Gram-negative bacteria Anatol Luther, Matthias Urfer, Michael Zahn, Nature Gram-negative BacteriologyAntibioticsAntibiotic AdjuvantChimeric Peptidomimetic AntibioticsAntibacterial Agent	2019	307
A single amino acid substitution in Staphylococcus aureus dihydrofolate reductase determines trimethoprim resistance 1 1 Edited by T.Richmond Glenn E. Dale, Clemens Broger, Allan D' Arcy, Journal of Molecular Biology Antimicrobial Resistance GeneBiochemistryNatural SciencesMolecular BiologyMicrobiology	1997	177
Peptide Deformylase as an Antibacterial Drug Target: Target Validation and Resistance Development Christian Apfel, Hans H. Locher, Stefan Evers, Antimicrobial Agents and Chemotherapy Bioorganic ChemistryPeptide EngineeringAntibacterial ActivityDrug ResistanceResistance Development	2001	126
Hydroxamic Acid Derivatives as Potent Peptide Deformylase Inhibitors and Antibacterial Agents Christian Apfel, David W. Banner, Daniel Bur, Journal of Medicinal Chemistry Antibacterial AgentsAntimicrobial ChemotherapyChemical BiologyBeta-sulfinylhydroxamic Acid DerivativesDrug Resistance	2000	111
<i>In Vitro</i>and<i>In Vivo</i>Antibacterial Evaluation of Cadazolid, a New Antibiotic for Treatment of Clostridium difficile Infections Hans H. Locher, Peter Seiler, Xinhua Chen, Antimicrobial Agents and Chemotherapy	2013	89
4-Sulphobenzoate 3,4-dioxygenase. Purification and properties of a desulphonative two-component enzyme system from <i>Comamonas testosteroni</i> T-2 Hans H. Locher, Thomas Leisinger, Alasdair M. Cook Biochemical Journal BiosynthesisEngineeringAldehyde DehydrogenaseBiochemistryNatural Sciences	1991	88
Potent Algicides Based on the Cyanobacterial Alkaloid Nostocarboline Judith F. Blom, Tobias Michael Brütsch, Damien Barbaras, Organic Letters	2006	78
Design, Synthesis and Biological Evaluation of Oxazolidinone–Quinolone Hybrids Christian Hubschwerlen, Jean-Luc Specklin, Christine Sigwalt, Bioorganic & Medicinal Chemistry PharmacologyOxazolidinone–quinolone HybridsBioorganic ChemistryNatural Product Synthesis	2003	78
Investigations of the Mode of Action and Resistance Development of Cadazolid, a New Antibiotic for Treatment of Clostridium difficile Infections Hans H. Locher, Patrick Caspers, Thierry Bruyère, Antimicrobial Agents and Chemotherapy Antibacterial AgentsAntimicrobial ChemotherapyAntibiotic ResistanceProtein SynthesisDrug Resistance	2013	76
Novel Dihydrofolate Reductase Inhibitors. Structure-Based versus Diversity-Based Library Design and High-Throughput Synthesis and Screening Pierre C. Wyss, Paul R. Gerber, Peter Hartman, Journal of Medicinal Chemistry Combinatorial ChemistryAntibacterial ActivityOrganic ChemistryChemical BiologyPharmaceutical Chemistry	2003	70

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