Daniel Bur

Novel Inhibitors of DNA Gyrase:  3D Structure Based Biased Needle Screening, Hit Validation by Biophysical Methods, and 3D Guided Optimization. A Promising Alternative to Random Screening

Hans-Joachim Boehm, Markus Boehringer, Daniel Bur et al. · Journal of Medicinal Chemistry · 2000 · 378 citations

Drug Target, Biochemistry, Hit Validation +15

Optically Active Bipyridines in Asymmetric Catalysis

Carsten Bolm, Margareta Zehnder, Daniel Bur · Angewandte Chemie International Edition in English · 1990 · 206 citations

Engineering, Active Bipyridines, Alkene Metathesis +11

2-Imino-thiazolidin-4-one Derivatives as Potent, Orally Active S1P₁Receptor Agonists

Martin H. Bolli, Stefan Abele, Christoph A. Binkert et al. · Journal of Medicinal Chemistry · 2010 · 173 citations · Full text

Molecular Pharmacology, 2-Imino-thiazolidin-4-one Derivatives, G Protein-coupled Receptor +13

The Discovery of <i>N</i>-[5-(4-Bromophenyl)-6-[2-[(5-bromo-2-pyrimidinyl)oxy]ethoxy]-4-pyrimidinyl]-<i>N</i>′-propylsulfamide (Macitentan), an Orally Active, Potent Dual Endothelin Receptor Antagonist

Martin H. Bolli, Christoph Boss, Christoph A. Binkert et al. · Journal of Medicinal Chemistry · 2012 · 146 citations · Full text

Hypertension, High Oral Efficacy, Compound 17 +18

Renin inhibition by substituted piperidines: A novel paradigm for the inhibition of monomeric aspartic proteinases?

Christian Oefner, Alfred Binggeli, Volker Breu et al. · Chemistry & Biology · 1999 · 126 citations · Full text

Inhibitory Activity, Medicinal Chemistry, Bioorganic Chemistry +12